Real world research without the bloat
Fast, affordable, non‑CTIMP and real‑world studies for teams who need credible evidence, not bureaucracy and inflated costs.
Food / drinks & dietary supplements
Healthy volunteers or targetted cohorts
Fully flexible trial design
Seamless wearables data capture
End-to-end and affordable
The traditional CRO model is broken
Large CROs stack layers of managers and reviewers onto every study, creating handovers and meetings that slow decisions, blur accountability and inflate costs without improving the science. At the same time, work passes through multiple intermediaries, each adding a margin, so even simple real‑world studies end up costing far more than the underlying work.
Their tech stacks are often a tangle of overlapping legacy systems and point solutions, dragging even simple observational studies into heavy, expensive infrastructure they don’t need. Without in‑house software expertise, they rely on generic tools and external vendors, making it hard to automate, streamline or cut waste, so digital workflows and costs are dictated by tool limitations rather than the study’s real needs.
Because their models, SOPs and commercial structures are built around large, complex CTIMPs, they struggle to strip things back to the essentials, making truly quick, pragmatic and affordable real‑world studies very hard to deliver within their usual timelines and fees.
A familiar story?
"We wanted to run something really simple to help us keep our competitive edge in the nutraceutical space. A few hundred healthy volunteers... some basic validated questionnaires... over a few weeks or months... Quotes from the usual CROs were coming in at over £1 million.
Something must be broken somewhere to create such staggering figures..."
We're built very differently
We were built specifically for lean, real‑world research rather than blockbuster CTIMPs, so our structures, processes and pricing are aligned with observational and pragmatic studies from day one. Instead of layers of junior staff and rigid templates, you get direct access to senior experts, flexible methods and light‑touch operations that keep studies moving quickly without unnecessary cost.
We focus on stable teams, clear communication and transparent timelines, offering a specialist alternative to the bloated one‑stop‑shop model and making high‑quality real‑world evidence genuinely accessible.
What we can do
We were built specifically for lean, real‑world research rather than blockbuster CTIMPs, so our structures, processes and pricing are aligned with observational and pragmatic studies from day one. Instead of layers of junior staff and rigid templates, you get direct access to senior experts, flexible methods and light‑touch operations that keep studies moving quickly without unnecessary cost.
We focus on stable teams, clear communication and transparent timelines, offering a specialist alternative to the bloated one‑stop‑shop model and making high‑quality real‑world evidence genuinely accessible.
Female Health
We run focused women’s health studies including menstrual and perimenopause.
Gut Health
We target gut symptom tracking in healthy volunteers or unique self-reported cohorts.
Stress & Mood
We support studies on stress and low mood, to address everyday mental wellbeing.
Nutrition
Leverage validated questionnaires, food intake and FFQs to produce meaningful results.
A lean and budget-friendly solution - end-to-end ... and without the price tag
Study protocol - flexible and accommodating
Study registration, approvals and ethics
Recruitment, onboading and eConsent
Monitoring, oversight and safety
How we keep things simple
We keep things simple with a lean team and deep in‑house expertise, avoiding unnecessary layers and complexity. That means costs and mark‑ups stay focused on delivery, not overhead.
In-house experts
Decades of clinical and real‑world evidence experience from an agile, efficient team delivering projects for CROs, pharma, biotech, and academia.
In-house ethics
Leverage the UK’s only in‑house ethics committee fully compliant with GDPR and GCP, ensuring gold‑standard, ethically robust real‑world evidence.
In-house tech
Powered by Trialflare, we use web and smartphone apps with rich integrations to wearables and app‑based cognitive tests for continuous, real‑world data.
We know real-world research
If you would like more information or for us to provide a rough cost for your next study, please reach out to the team
hello@cometclinical.com
